CureMatch is a service that customizes the right combination(s) of cancer therapies to match the molecular makeup of your individual tumor, in order to hit as many genetic biomarkers driving your cancer as hard as possible.

With the help of CureMatch’s expertly curated knowledge base and AI-powered proprietary algorithm, we match the best drug combinations to fight your tumor.  We customize treatment options for you by sorting through millions of drug combinations.  We then filter, rank, and score the best possible combinations that match your individual tumor so there may be a higher chance of progression-free survival (PFS) and overall survival (OS).

Your CureMatch result will provide additional information for your doctor when they are considering the best possible treatment for you, based on all of the genetic information they provide to CureMatch.

The CureMatch Result includes:

• CureMatch Matches, ranks, and scores both known and novel combination therapies, with the medical and scientific rationale included for all matches (FDA-approved and EMA-label for International)
  • Top 3 Matching 3-drug combinations
  • Top 3 Matching 2-drug combinations
  • Top 3 Matching monotherapies (1-drug)
• Exclusions / Warnings Page shows the therapeutic drugs that do not go well together in combinations (caution should be taken) and the rationale behind each one
• “Physician’s Selection” provides an opportunity for us to score, separately, the specific therapy or combination of therapies that your doctor is thinking of putting you on to see how it compares to CureMatch’s scores.
• Alternative Drug Choices provide the therapeutic options that may have alternative drug choices. Drugs are considered alternatives when they share the same analogous mechanisms of action and impact on the score with
  • The same targeting mechanisms
  • The same therapy class
  • The same score
• Black-Box Warning, Contraindications, and Examples of Drug-Drug Interactions will be shown, if any
• Examples of Existing Clinical Trials using matched drugs, if any available

*The analysis that CureMatch provides is based on the actionable biomarkers of your Next Generation Sequencing (NGS) Somatic Tumor Profile results.  Not all patients have more than one (1) actionable biomarker.  If CureMatch only finds one (1) actionable biomarker, a CureMatch Report would not offer additional value, due to the lack of additional therapy options to consider.

The CureMatch Analysis needs to be ordered by your Oncologist. Once you have had your Next Generation Sequencing (NGS) Tumor Profiling or Liquid Biopsy done, those results can be sent to CureMatch, via our secure Physician Portal, and will be analyzed using our proprietary Artificial Intelligence (AI) – powered algorithm.

Here are the steps involved:

1. Your Tumor Biopsy or Liquid Biopsy Results from your clinic/hospital are uploaded by your care team into CureMatch’s Physician Portal
2. CureMatch Analyzes your tumor and/or liquid biopsy results with their AI-powered algorithm, filtering through 300+ FDA and EMA approved oncology drugs, which is roughly 4.5 million combinations
3. CureMatch Customizes the best combinations of drugs possible that are matched to the molecular make-up of your individual tumor
4. The CureMatch Report is sent to your care team for your doctor to consider the best possible treatment for you
5. The Doctor from Your Care Team will review the results with you

We strive to complete the CureMatch Analysis within 3 business days after receiving the required information from the lab and/or your doctor.  The results will be made available to your doctor through their secure CureMatch Physician Portal.  The result is made available in a PDF format so you and your doctor can evaluate the information and choose a treatment plan together.

CureMatch is currently not covered by insurance. However, patients may pay cash for this service, or you can have someone provide you with the Gift of CureMatch via the link here.

The cash pay price for patients is $1,500 out-of-pocket for the CureMatch Report

CureMatch looks at a variety of sources when customizing your matched treatments.  Along with the curated knowledge base of scientific, medical, and clinical evidence, the sources include:

• Your Next Generation Sequencing (NGS) tumor profile and / or Liquid Biopsy report(s) (Required)
• Any of your Pathology Reports (with Biomarker Identification), RNA, Protein or Immune Marker Reports, and Pharmacogenomic Testing Reports, if available
• 300+ FDA and EMA approved cancer drugs
• Published clinical genomic evidence
• Pharmacology
  • Drug mechanisms
  • Drug labels
• Clinical Trials

The CureMatch Analysis is available for patients with all types of cancer, at all stages of the disease, and at any time during the course of treatment.  While it is best to get a CureMatch Analysis done soon after diagnosis, in some cases a patient may already be undergoing some type of therapy.  We believe that any patient about to get molecular testing done, like Next Generation Sequencing (NGS) Tumor Profiling or Liquid Biopsies, deserves to be “CureMatched” as the next logical step.

Yes, a CureMatch Analysis can be performed on children with cancer.  Reports for children ages 18 and under are available at no charge.

Once you have your Gift of CureMatch purchased, have your voucher information available and call 858-924-8490 or email us at ProgramCoordinator@CureMatch.com

A Program Coordinator will be assigned to schedule an introductory call.  Your Program Coordinator will reach out to help connect with your doctor to ensure you have the required lab tests completed in order to run your CureMatch Analysis.